Showing posts with label Pathology. Show all posts
Showing posts with label Pathology. Show all posts

What is the difference between metastatic and dystrophic calcification?

What is the difference between metastatic and dystrophic calcification?




Answer:

Metastatic calcification: Deposition of calcium in Normal tissue due to hyperglycaemic state. E.g. in normal conjunctiva.
Dystrophic calcification: Deposition of calcium in hyalinised or necrotic tissue in a normocalcemic state. E.g. calcified TB in lungs, phthisis bulbi

What is seen microscopically in posterior polymorphous dystrophy (endothelial)?

What is seen microscopically in posterior polymorphous dystrophy (endothelial)?



Answer: The posterior surface of the cornea is lined with cells that resemble epithelial cells, with intracytoplasmic filaments and desmosomal attachments. There is an abnormal collagen layer on the posterior surface of the original Descemet's membrane.

Describe 3 conditions with which iridocorneal endothelial syndrome is associated.

Describe 3 conditions with which iridocorneal endothelial syndrome is associated.



Answer:

1) Essential iris atrophy (progressive iris stromal atrophy)
2) Chandler syndrome: Glaucoma due to endothelial sliding over TM, normal iris.
3) Iris naevus syndrome : Occurring with iris naevus.